Shaping the digital future of chemistry demands a diverse and powerful toolkit. Among these, Statistical Design of Experiments (DOE), a proven method from the analogue era, remains a vital but underutilised approach for speeding innovation in chemical process development.
Modern DOE software empowers scientists and engineers to statistically design customised experiments that consider the real-world challenges and limitations which are inherent to process chemistry. This workshop will provide hands-on experience of the design, evaluation and analysis of experiments. With a focus on the application of modern DOE software in simulated process chemistry challenges, the workshop is suitable for those new to the method, and those with some prior experience who want to begin exploring more complex scenarios.
Learning Outcomes
Dr Benjamin J. Deadman is an independent Consultant Scientist specialising in the advanced analysis of chemical reaction processes. He provides expert consultation, advanced training, and contract research services in Design of Experiments (DOE), High-Throughput Experimentation (HTE), flow chemistry and reaction analysis.
Previously Ben was the founding Facility Manager of the Centre for Rapid Online Analysis of Reactions (ROAR), a shared state-of-the-art facility providing the UK chemical R&D community with the tools and expert support needed to perform data-rich experimentation in chemistry. It was during his years at ROAR that Ben developed and fine-tuned his approach to teaching holistic DOE for chemistry, through hands-on, simulated process chemistry challenges.
Ben received an MSc from the University of Waikato (New Zealand) before moving to the University of Cambridge (UK) as a Commonwealth Scholar in 2009. After completing his PhD under the supervision of Prof. Steven Ley in 2013 he moved to University College Cork (Ireland) to work with Prof. Anita Maguire as a Postdoctoral Research Associate of the Synthesis and Solid State Pharmaceutical Centre (SSPC). Then, prior to establishing ROAR, Ben was a Research Associate (2015 to 2017) working with Prof. King Kuok (Mimi) Hii and Prof. Klaus Hellgardt on the application of electrochemically generated oxidants in organic synthesis.
Modern DOE software empowers scientists and engineers to statistically design customised experiments that consider the real-world challenges and limitations which are inherent to process chemistry. This workshop will provide hands-on experience of the design, evaluation and analysis of experiments. With a focus on the application of modern DOE software in simulated process chemistry challenges, the workshop is suitable for those new to the method, and those with some prior experience who want to begin exploring more complex scenarios.
Learning Outcomes
- Formulate experimental problems so that they can be tackled by optimal DOE
- Apply JMP software to design a custom experiment to answer target questions
- Evaluate and compare experimental designs
- Analyse and interpret experimental results using ANOVA and linear regression
Dr Benjamin J. Deadman is an independent Consultant Scientist specialising in the advanced analysis of chemical reaction processes. He provides expert consultation, advanced training, and contract research services in Design of Experiments (DOE), High-Throughput Experimentation (HTE), flow chemistry and reaction analysis.
Previously Ben was the founding Facility Manager of the Centre for Rapid Online Analysis of Reactions (ROAR), a shared state-of-the-art facility providing the UK chemical R&D community with the tools and expert support needed to perform data-rich experimentation in chemistry. It was during his years at ROAR that Ben developed and fine-tuned his approach to teaching holistic DOE for chemistry, through hands-on, simulated process chemistry challenges.
Ben received an MSc from the University of Waikato (New Zealand) before moving to the University of Cambridge (UK) as a Commonwealth Scholar in 2009. After completing his PhD under the supervision of Prof. Steven Ley in 2013 he moved to University College Cork (Ireland) to work with Prof. Anita Maguire as a Postdoctoral Research Associate of the Synthesis and Solid State Pharmaceutical Centre (SSPC). Then, prior to establishing ROAR, Ben was a Research Associate (2015 to 2017) working with Prof. King Kuok (Mimi) Hii and Prof. Klaus Hellgardt on the application of electrochemically generated oxidants in organic synthesis.
